Categories: High Phenolic EVOO

by athan

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Categories: High Phenolic EVOO

by athan

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The more the phenolic compound oleocanthal is studied the more it is found to contain unique health benefits. Beyond just being a food source Greek olive oil rich in oleocanthal has a powerfull anti inflammatory effect that can be measured and verified. The study below is another step forward in our understanding oleocanthals’ wide array of potential health benefits.

http://www.oliveoiltimes.com/olive-oil-health-news/olive-oil-polyphenol-positively-impacts-human-melanoma-cells/52838

Olive Harvest in Ancient Hellenic Culture

Ancient Greek culture used early harvest olive oil as a medicine. Is it any wonder why oleocanthal is the mosty prolific phenolic compound found in modern Greek olive oils?

Abstract: http://www.ncbi.nlm.nih.gov/pubmed/27266366

Oleocanthal is one of the phenolic compounds of extra virgin olive oil with important anti-inflammatory properties. Although its potential anticancer activity has been reported, only limited evidence has been provided in cutaneous malignant melanoma. The present study is aimed at investigating the selective in vitro antiproliferative activity of oleocanthal against human malignant melanoma cells. Since oleocanthal is not commercially available, it was obtained as a pure standard by direct extraction and purification from extra virgin olive oil. Cell viability experiments carried out by WST-1 assay demonstrated that oleocanthal had a remarkable and selective activity for human melanoma cells versus normal dermal fibroblasts with IC50s in the low micromolar range of concentrations. Such an effect was paralleled by a significant inhibition of ERK1/2 and AKT phosphorylation and downregulation of Bcl-2 expression. These findings may suggest that extra virgin olive oil phenolic extract enriched in oleocanthal deserves further investigation in skin cancer.

DISCLAIMER: Οι πληροφορίες και οι απόψεις που αναφέρονται στο παρόν άρθρο είναι αυτές του συγγραφέα και δεν απηχούν κατ ‘ανάγκη την επίσημη γνώμη της Aristoleo Ltd ή Artemis Allianceα Inc.. Ούτε Aristoleo Ltd ή Artemis Allianceα Inc. ή οποιοδήποτε πρόσωπο που ενεργεί για λογαριασμό τους, μπορεί να θεωρηθούν υπεύθυνοι για τη χρήση που μπορεί να γίνει των πληροφοριών που περιέχονται σε αυτήν.

The information and views set out in this article are those of the author and do not necessarily reflect the official opinion of the Aristoleo Ltd or Artemis Alliance Inc. . Neither Aristoleo Ltd or Artemis Alliance Inc. any person acting on their behalf may be held responsible for the use which may be made of the information contained therein.

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