Dr Prokopios Magiatis and Dr. Eleni Melliou

Oleocanthal in Olive Oil Lowers White Blood Cells in People Diagnosed with Chronic Lymphocytic Leukemia

Good news for people suffering with Chronic Lymphocytic Leukemia (CLL). Initial randomized Pilot Study with human volunteers has shown that Oleocanthal rich olive oil reduces White Blood Cells (WBC) in CLL patients not under any medication but under doctors supervision as their WBC was rising. Once they began daily consumption of 40ml of high oleocanthal olive oil their WBC began to be reduced.

Read the press release and the research paper below. The data makes a compeling case for further research. I was asked if people diagnosed with CLL and not under any medication should begin consuming 40ml a day of high oleocanthal olive oil. This is something they need to discuss with their doctor, so that if they do decide to try it it can be monitored.

This is a very promising area of research and I believe it will have far reaching positive results for all concerned; the olive growers, the scientists and most importantly the patients themselves. Although very positive it is not considered be definitive evidence of a new treatment for CLL but it does ensure more clinical trials will be conducted to better understand this initial finding.


OLIVE LAB AND SHOP in Athens Greece https://olivelabandshop.com/en


All content found on the Aristoleo.com website, including: text, images, audio, or other formats is created for informational purposes only.
Content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on this website.


Athens, Jan 27, 2022 – World Olive Center for Health (WOCH), a non-profit organization based in Athens Greece, announces a breakthrough in understanding the effect of specific phenolic compounds in olive oil on Chronic Lymphocytic Leukemia (CLL) following a randomized Pilot Study with human volunteers.

This human volunteer pilot study trial consisted of 22 patients diagnosed with early-stage CLL under medical supervision. Their white blood cell count was rising but were under no medication. The results were recently published in the respected medical journal Frontiers in Oncology: https://www.frontiersin.org/articles/10.3389/fonc.2021.810249/full

Dr. Eleni Melliou pointed out: “It is the first time that we were able to show that oral administration of a daily dose of 25 mg oleocanthal and oleacein through the consumption of 40 mL of Extra Virgin Olive Oil for a six-month period could be beneficial for CLL patients, reducing white blood cell count, inducing the apoptosis of their cancer cells, and improving the metabolism of the patients.”

The Pilot Study was a collaboration between Dr. Prokopios Magiatis and Dr. Eleni Melliou from the National and Kapodistrian University of Athens and WOCH, Dr. Andrea Paola Rojas from the Univ. of Peloponnese, Dr. Kodonis at Hospital of Lakonía, Dr. Nomikos from the Harokopio Univ. and their research team A. Ioannidis, I. Dimopoulos, G. Kosmidis, M. Katsa.

Dr. Prokopios Magiatis and Dr. Eleni Melliou initiated the study after receiving feedback from people suffering with CLL claiming their white blood cell count declined after beginning to consume olive oil rich in oleocanthal and oleacein.

WOCH funded this study from income entirely derived from membership fees and from analyzing phenolic concentrations in olive oil using quantitative Nuclear Magnetic Resonance (qNMR) and private donations. The qNMR method was developed in 2012 by Magiatis/Melliou and their team of researchers at the Univ. of Athens.

One of our main targets was to investigate the hypothesis that the biological activity of olive oil against cancer is related to its content, in specific phenolic ingredients and especially in oleocanthal and oleacein, as we had recently shown for the inhibition of platelet aggregation (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995573/) and for the improvement of cognitive function in people with mild cognitive impairment: (https://pubmed.ncbi.nlm.nih.gov/33044178/)” Dr. Magiatis explained.

The complex mechanisms regarding the progression of CLL disease appear to benefit from the anticancer properties of the phenolic compounds, oleocanthal and/or oleacein.

Dr Paola Rojas clarified: “The results of this pilot study should not be used as a proof of efficacy but as a proof that the study can and is worthy to be expanded to a multi-center larger trial.”

World Olive Center for Health website:


Magiatis video presentation: https://youtu.be/AdU2tLxym6g


Dr. Prokopios Magiatis
Tel: +30 2107010131
Athens Greece



Dr. Melliou Eleni

Dr. Eleni Melliou


Dr. Prokopios Magiatis

Dr. Prokopios Magiatis


Subscribe to our free newsletter.

Don’t have an account yet? Get started with a 12-day free trial

Leave A Comment

Related Posts